1. A 50-year-old man with fibrotic NSIP is being treated
with oral corticosteroids and cyclophosphamide. After 6 months of therapy, he
begins to report progressive breathlessness. Why is this occurring?
2. A 30-year-old woman has ILD and is a current smoker. She
is concerned that quitting on her own is too difficult and comments that
tobacco use is associated with emphysema, not with scarring. Should she be
encouraged to quit smoking? Why or why not?