1. A 51-year-old wom an, recently diagnosed w ith Paget disease of bone, had been receiving…

1. A 51-year-old wom an, recently diagnosed w ith Paget disease of bone, had been receiving alendronate for 1 week, but the drug had to be suspended because of a persistent abdom inal pain. The physician decided to replace the alendronate w ith calcitonin. Which of the follow ing actions m ost likely m ediated the therapeutic e ect of calcitonin in the patient’s disease? A. Inhibition of osteoclast activity B. Stim ulation of osteoblast activity C. Stim ulation of renal calcium reabsorption D. Stim ulation of renal phosphate reabsorption E. Inhibition of intestinal calcium absorption

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