1. Can jaundice occur early in schistosomal hepatic fibrosis and, if so, how? 2. My patient has been

1. Can jaundice occur early in schistosomal hepatic fibrosis and, if so, how? 2. My patient has been found to have a serum bilirubin of 34 µmol/L (2mg/dL) on three occasions. The other liver tests are normal. He tells me he has Gilbert’s disease; how can I prove this? 3. Why is urinary urobilinogen increased in haemolytic jaundice? If the bilirubin in this condition is unconjugated, how does it reach the terminal ileum to be converted into urobilinogen?

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