1. Is there any rationale for giving either propranolol, valproate or buspirone to patients with…

1. Is there any rationale for giving either propranolol, valproate or buspirone to patients with cerebellar ataxia? 2. Is there a laboratory marker for cerebral dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)? Is serum lactic acid elevated? 3. Primary brain tumours rarely metastasize outside the brain but malignancies outside the brain frequently metastasize to the brain. Why?

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