1. Obese people have leptin resistance due to which they do not respond to leptin when it is…

1. Obese people have leptin resistance due to which they do not respond to leptin when it is administered as pharmacotherapy. Which of the following factors has been definitively implicated as a cause of leptin resistance in humans? A. Mutated leptin receptor B. Decreased levels of adiponectin C. Defect in leptin signaling D. Mutated leptin gene

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