1. The gure below depicts the concentration-tim e curve of a new drug after a single intravenous…

1. The gure below depicts the concentration-tim e curve of a new drug after a single intravenous dose of 20 m g was adm inistered to a laboratory anim al. W hich of the follow ing drugs does the new agent m ost resem ble? A. Atropine B. Propranolol C. Ethanol D. Phenylephrine E. Clonidine F. Dobutam ine 2. The pharm acokinetics of a new drug was studied in a healthy volunteer. The drug followed rst-order, one-com partm ent m odel kinetics and had a half-life of 3 hours. An intravenous infusion of the drug was started at 8:00 a.m . A blood sam ple taken at 2:00 p.m . of the sam e day showed a plasm a drug concentration of 60 µg/m L. Which of the follow ing was m ost likely the plasm a concentration of that drug (in µg/m L) at the steady state? A. 100 B. 60 C. 80 D. 30 E. 40 F. 120

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