1. The gure below depicts the plasm a concentration-tim e curves for four drugs (W, X, Y, and Z)…

1. The gure below depicts the plasm a concentration-tim e curves for four drugs (W, X, Y, and Z) given by IV infusion to the sam e laboratory anim al on four separate occasions Which of the follow ing drugs has the shortest half-life? A. Drug W B. Drug X C. Drug Y D. Drug Z 2. The pharm acokinetics of a new drug was studied in a healthy volunteer. The drug w as given by intravenous infusion at a rate of 30 m g/h. The plasm a concentration-tim e curve of the drug is depicted below. Which of the follow ing is m ost likely the total clearance of the drug (in L/h)? A. 4 B. 6 C. 2 D. 10 E. 14 F. 16

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