1. What is the difference between the management of a gastric and of a duodenal ulcer? 2. How does..

1. What is the difference between the management of a gastric and of a duodenal ulcer? 2. How does omeprazole suppress Helicobacter pylori ? 3. Does omeprazole cause rebound hyperacidity? Does this also apply to H2-blockers? 4. On ( K&C 7e, p. 249 ), you state that the postsynaptic neurotransmitter that inhibits the relaxation of lower oesophageal sphincter (LOS) is nitric oxide (NO). I have understood NO to promote relaxation of LOS by acting on the non-adrenergic, non-cholinergic (NANC) inhibitory neurones, which inhibits the action of cholinergic excitatory neurones. Could you please explain this paradox?

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