1. What is the difference in efficacy and pharmacokinetics between sodium valproate and valproic…

1. What is the difference in efficacy and pharmacokinetics between sodium valproate and valproic acid? 2. Is it safe to give valproic acid to infants below 12 months of age? 3. How many times must the liver transaminases (SGOT and SGPT) rise to justify a discontinuation of valproic acid therapy in children? Which of these enzymes is more sensitive and reliable in this situation?

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