A 17-year-old boy drank increasing am ounts of alcohol w hen attending parties. He noticed that…

A 17-year-old boy drank increasing am ounts of alcohol w hen attending parties. He noticed that lately he was able to better tolerate alcohol e ects and asked his physician the reason for this. The physician said that pharm acodynam ic tolerance had probably occurred. Which of the follow ing actions m ost likely m ediated this tolerance? A. Decreased concentration of the drug at the site of action B. Hom eostatic adaptive changes that counteract the drug e ect C. Decreased bioavailability of the drug D. Increased biotransform ation of the drug E. Increased num ber of drug receptors

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