A 17-year-old girl started sm oking 1 m onth ago, and now she is sm oking 5 to 10 cigarettes daily..

A 17-year-old girl started sm oking 1 m onth ago, and now she is sm oking 5 to 10 cigarettes daily. She has noticed that the rst cigarette of the day often causes m ild tachycardia, w hich does not usually occur w ith the follow ing cigarettes. W hich of the follow ing term s best de nes this tolerance pattern? A. Cross-tolerance B. Tachyphylaxis C. Pharm acokinetic tolerance D. Innate tolerance E. Sensitization

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