A 22-year-old wom an w ith t ype 1 diabetes was brought unconscious to the em ergency departm ent…

A 22-year-old wom an w ith t ype 1 diabetes was brought unconscious to the em ergency departm ent. Her blood glucose level was 395 m g/dL (norm al 70-110 m g/dL). An intravenous infusion of insulin was started, and 6 hours later the patient’s blood glucose decreased to a norm al level. Which of the follow ing m olecular actions m ost likely contributed to the therapeutic e ect of the drug in the patient’s disorder? A. Inhibition of glucose transporters in pancreas cell membranes B. Phosphorylation of a tyrosine kinase-linked receptor C. Activation of adenosine triphosphate (ATP)-sensitive K+ channels in target cells D. Stim ulation of horm one-sensitive lipase E. Inhibition of liver glucokinase

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