A 32-year-old m ale cocaine addict was brought unconscious to the em ergency departm ent. A friend..

A 32-year-old m ale cocaine addict was brought unconscious to the em ergency departm ent. A friend stated that the m an had intravenously self-injected an unknow n dose of cocaine 2 hours earlier. An im m ediate lab analysis indicated that the plasm a level of cocaine was 0.75 m g/L. Cocaine has a volum e of distribution of about 130 L and a half-life of about 1 hour. Which of the follow ing was m ost likely the injected dose of cocaine (in m g)? A. 250 B. 390 C. 420 D. 315 E. 180 F. 115

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