A 32-year-old pregnant wom an was found to have a red blood cell count of 3.2 × 106/mm3 (norm al…

A 32-year-old pregnant wom an was found to have a red blood cell count of 3.2 × 106/mm3 (norm al 3.5-5.5 × 106) and a positive direct Coom bs test during a regular clinic visit. The wom an had started a treatm ent w ith m ethyldopa 4 m onths earlier because of stage 1 hypertension. Which of the following m echanism s m ost likely m ediated the drug-induced reaction of this patient? A. De ciency of the reduced form of nicotinam ide adenine dinucleotide (NADH)-m ethem oglobin reductase B. Production of autoantibodies against red blood cells C. Drug-induced de ciency of folic acid D. Drug-induced bone m arrow suppression E. De ciency of glucose-6-phosphate dehydrogenase

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