A 43-year-old m an was brought to the em ergency room follow ing a car accident. He received an in..

A 43-year-old m an was brought to the em ergency room follow ing a car accident. He received an in ltration of a local anesthetic around a skin wound in preparation for suturing. A few m inutes later, the m an appeared ushed and com – plained of di culty breathing. Blood pressure was 90/50 m m Hg, heart rate 92 bpm . Chest auscultation revealed restrictive air ow and stridor. An injection of epinephrine was given. Which of the follow ing actions m ost likely contributed to the therapeutic e cacy of the drug in the patient’s disorder? A. Antagonism of histam ine e ects on the heart B. Antagonism of bradykinin e ects on skeletal m uscle vessels C. Antagonism of leukotriene e ects on the respiratory system D. Activation of a1 receptors on bronchial m uscles E. Activation of ß2 receptors on lung vessels F. Activation of a2 receptors on platelets

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