A 44-year-old wom an su ering from open-angle glaucom a had been receiving topical tim olol for 3 m.

A 44-year-old wom an su ering from open-angle glaucom a had been receiving topical tim olol for 3 m onths. The disease was well controlled, and the treatm ent stopped the progression of optic nerve dam age. Which of the follow ing m olecular actions m ost likely m ediated the therapeutic e cacy of the drug in the patient’s disease? a. Opening of ligand-gated K+ channels b. Increased synthesis of diacylglycerol (DAG) c. Decreased synthesis of cyclic guanosine m onophosphate (cGMP) d. Decreased activity of adenylate cyclase e. Increased synthesis of tyrosine kinase f. Opening of ligand-gated Na+ channels

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