A 45-year-old wom an recently diagnosed w ith a urinary tract infection started therapy w ith a trim

A 45-year-old wom an recently diagnosed w ith a urinary tract infection started therapy w ith a trim ethoprim -sulfam ethoxazole com bination. Both trim ethoprim and sulfam ethoxazole are bacteriostatic drugs w hen given alone. However, a bactericidal e ect is obtained w hen the two drugs are given in com bination. Which of the follow ing term s best de nes this drug interaction? A. Additive e ect B. Potentiation C. Synergism D. Reverse tolerance E. Sensitization

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