A 46-year-old wom an su ering from polyarteritis nodosa, an autoim m une disease, had been receiving

A 46-year-old wom an su ering from polyarteritis nodosa, an autoim m une disease, had been receiving high-dose dexam ethasone. Which of the follow ing actions m ost likely contributed to the therapeutic e ect of the drug in the patient’s disease? A. Inhibition of catabolism of prostaglandins B. Inhibition of liver protein synthesis C. Increased proliferation of B cells D. Increased activation of com plem ent system E. Inhibition of catabolism of interleukin-1 F. Inhibition of synthesis of tum or necrosis factor (TNF)

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