A 47-year-old m an was adm itted to the em ergency departm ent because of extrem e m uscle weakness,

A 47-year-old m an was adm itted to the em ergency departm ent because of extrem e m uscle weakness, ptosis, diplopia, and di culty in swallow ing, speaking, and breathing. The m an, recently diagnosed w ith severe myasthenia gravis, had been receiving neostigm ine for the past 3 m onths. Which of the follow ing responses to 2 mg of intravenous edrophonium would indicate a cholinergic crisis? a. No fasciculations, increased m uscle strength b. Fasciculations, decreased m uscle strength c. No fasciculations, no change in m uscle strength d. No fasciculations, decreased m uscle strength e. Fasciculations, increased m uscle strength

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