A 57-year-old m an w ho was in the hospital after a surgical procedure com plained of a severe abdom

A 57-year-old m an w ho was in the hospital after a surgical procedure com plained of a severe abdom inal pain. The physician decided to start analgesic treatm ent w ith an opioid. The drugs he was considering were m orphine (10 m g IM) and buprenorphine (0.3 m g IM). Morphine is a full agonist at m u (µ) opioid receptors, w hereas buprenorphine is a partial agonist at the sam e receptors. The above-m entioned doses of the two drugs are equie ective. Which of the follow ing pairs of statem ents correctly de nes the potency and e – cacy of m orphine and buprenorphine? A. Morphine is m ore potent. Buprenorphine is m ore effective. B. Morphine is m ore potent. Buprenorphine is less effective. C. Morphine is less potent. Buprenorphine is m ore effective. D. Morphine is less potent. Buprenorphine is less e ective.

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