A 68-year-old m an w ith a long history of chronic cardiac failure presented to his physician com…

A 68-year-old m an w ith a long history of chronic cardiac failure presented to his physician com plaining of urinary hesitancy and frequent need to urinate during the night. An exam ination revealed an enlarged prostate, and further exam s con rm ed the diagnosis of benign prostatic hyperplasia. Finasteride was included as part of his therapeutic regim en. Which of the follow ing actions m ost likely m ediated the therapeutic e ect of the drug in the patient’s disease? A. Inhibition of follicle-stim ulating horm one (FSH) and luteinizing horm one (LH) release B. Inhibition of gonadotropin-releasing horm one (GnRH) release C. Inhibition of 5a-reductase enzym e D. Blockade of progesterone receptors E. Blockade of testosterone receptors

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