A 75-year-old wom an com plained to her physician of increased need to urinate during the night. The

A 75-year-old wom an com plained to her physician of increased need to urinate during the night. The wom an had been receiving gentam icin for 2 m onths to treat a urinary tract infection. Lab tests revealed a serum creatinine level of 5 m g/dL (norm al 0.5-1.2 m g/dL). Serum gentam icin concentration obtained just before the last dose was 9 m g/dL (norm al A. Type II allergic reaction B. Type III allergic reaction C. Idiosyncratic reaction D. Pseudoallergic reaction E. Overdose toxicit y

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