A high dose of nicotine was adm inistered intravenously to dogs in a laboratory experim ent. An…

A high dose of nicotine was adm inistered intravenously to dogs in a laboratory experim ent. An initial increase in blood pressure was soon followed by a profound decrease of blood pressure. Which of the follow ing m olecular m echanism s m ost likely m ediated the decrease in blood pressure? a. Long-lasting activation of nicotinic neuronal receptors b. Long-lasting blockade of m uscarinic M2 receptors c. Long-lasting blockade of m uscarinic M1 receptors d. Prevention of acet ylcholine release from presynaptic term inals e. Prevention of catecholam ine release from chrom a n cells

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