It is stated that nitric oxide (NO) inhibits the relaxation of the lower oesophageal sphincter (LOS)

It is stated that nitric oxide (NO) inhibits the relaxation of the lower oesophageal sphincter (LOS) and that sildenafil is given for treating achalasia. As far as I know, sildenafil acts to increase the guanine monophosphate (GMP), just as NO uses the same mechanism to relax the LOS. Could you explain this paradox?

Don't use plagiarized sources. Get Your Custom Essay on
It is stated that nitric oxide (NO) inhibits the relaxation of the lower oesophageal sphincter (LOS)
For as low as $7/Page
Order Essay

Leave a Reply

Your email address will not be published. Required fields are marked *

*

*

*