The association of CFCs with degradation of the earth’s atmosphere and the ozone layer has resulted.

The association of CFCs with degradation of the earth’s
atmosphere and the ozone layer has resulted in an international treaty banning
use of these compounds. As HFAs become the propellants of choice, a problem
arises. If the CFC and HFA drug formulations are bioequivalent, can these
compounds be used with the same (universal) pMDI actuator, or boot

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